A Compherensive Review of the Anti-Obesity Properties of Medicinal Plants


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Authors

DOI:

https://doi.org/10.62482/pmj.10

Keywords:

Obesity, Pharmacological İnterventions, Plant Extracts, Metabolic Processes, Weight Management

Abstract

Obesity has emerged as a global health crisis, contributing to numerous comorbidities including diabetes, cardiovascular diseases, and chronic inflammation. Although lifestyle modifications are recommended to prevent obesity, the increase of obesity in last years has revealed the importance of drug research. While bariatric surgery remains an effective approach, the limited number of approved pharmacotherapies for obesity necessitates further investigation into novel therapeutic agents. Currently, there has been growing interest in exploring the potential of plant extracts in the treatment of obesity. Phytoextracts, derived from a variety of botanical sources, have attracted considerable attention due to their therapeutic properties and perceived lower risk profile compared to synthetic pharmaceuticals. These extracts often contain bioactive compounds such as polyphenols, flavonoids, and alkaloids, which have been extensively studied for their anti-obesity effects. Research indicates that certain plant extracts can modulate weight control by influencing metabolic processes, overall health, and lipid metabolism. The integration of herbal extracts into obesity treatment regimens offers a holistic approach to health, presenting a natural alternative to conventional medicine. Moreover, plant extracts often exhibit pleiotropic effects, targeting multiple pathways involved in the pathogenesis and progression of obesity. This multifaceted mechanism holds promise for enhancing clinical outcomes while minimizing the risks associated with monotherapy. However, despite regimens and potential, further research is essential to elucidate the precise mechanisms of action, optimize dosage regimens, and evaluate the long-term safety and efficacy of these interventions.

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2024-06-30

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Saglam, K., & Sekerler, T. (2024). A Compherensive Review of the Anti-Obesity Properties of Medicinal Plants. Pharmedicine Journal, 1(2), 46–67. https://doi.org/10.62482/pmj.10

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Review